High-affinity choline uptake protein bett

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August undefined, 2024

Web1 de abr. de 2024 · Furthermore, the genome contains nine genes related to the synthesis and transport of the compatible-solute glycine betaine for resistance to osmotic stress … WebCholine uptake is regulated by nerve impulses and trafficking of an intracellular pool of CHT1 to the plasma membrane may be important for this regulation. We have generated a hemagglutinin (HA) epitope tagged CHT1 to investigate the organelles involved with intracellular trafficking of this protein. Expression of CHT1-HA in HEK 293 cells ...

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Web29 de mar. de 2024 · This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from … WebHigh affinity choline uptake is generally believed to be the rate-limiting step in acetylcholine synthesis in cholinergic neurons and is essential for cholinergic ... hCHT1 protein is composed of 580 amino acids with a predicted molecular mass of 63 kDa. Sequence analysis of the hCHT1 protein predicts 13 transmembrane domains (13, 20, 21). dwarf fortress what to do with corpses

MKleb_1404 - High-affinity choline uptake protein BetT

Web1 de jan. de 2024 · The high-affinity choline uptake activity in patients with these diseases was predicted to be diminished by mutations that impaired CHT1 function and/or trafficking. There is a functionally relevant, nonsynonymous single nucleotide polymorphism in the coding region of the human CHT1 gene (c.265A>G, rs1013940) (Okuda et al. 2002 ). WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) WebStaphylococcus aureus; pan ID: SAUPAN006318000; symbol: cudT; products: choline transporter BetT, choline transporter, BCCT family choline/carnitine/betaine … crystal colored contact lenses

CHT1 (High-affinity Choline Transporter) SpringerLink

The ATP‐binding cassette transporter Cbc (choline…

WebIn cholinergic neurons, high-affinity choline uptake in presynaptic terminals is the rate-limiting step in acetylcholine synthesis. Using information provided by the … WebA molecular phylogenetic analysis of salt-tolerance-related genes was carried out using complete genome sequencing data available for 26 Sinorhizobium meliloti strains and for 25 bacterial strains belonging to 17 genera. It was revealed that the genes of the first and the second stages of the response to salt stress (aqpZ, trkH, and trkA, and betICBA) have … crystal color chartWebThe presumed binding proteins of both ABC transporters were shown to be lipoproteins. ... -choline uptake via OpuB (K(m) = 1 microM; Vmax = 21 nmol min-1 mg-1 protein) and OpuC (K(m) = 38 microM; Vmax = 75 nmol min-1 mg-1 protein) revealed that each of these ABC transporters exhibits high affinity and substantial transport capacity. crystal color changing lip gloss

"WebThe uptake of choline can occur via two transport systems, one that exhibits a high affinity for choline uptake (HAChU, K m =1–5 μM) and is dependent on both Na + and Cl −, and a second transporter system that has a significantly lower affinity for choline uptake (LAChU, K m =10–100 μM) and is independent of Na + and Cl − (see also Ch. 3). " - High-affinity choline uptake protein bett

High-affinity choline uptake protein bett

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Web1 de mar. de 2007 · For osmoprotection, Escherichia coli can synthesize glycine betaine from externally supplied choline by the Bet system (betTIBA products). The major carrier of choline is the high-affinity, proton-driven, secondary transporter BetT, which belongs to the BCCT family of transporters. Fusion proteins consisting of N-terminal fragments of … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. …

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Web8 de mar. de 2006 · The high-affinity choline transporter at the molecular level. Despite the fact that the high-affinity choline uptake system was described in the 1960s, the genes … WebHigh-affinity transport of choline-O-sulfate and its use as a compatible solute in Bacillus subtilis High-affinity transport of choline-O-sulfate and its use as a compatible solute in …

Web1 de jan. de 2024 · CHT1 has been functionally characterized by its capacity to transport choline with high affinity when expressed in cultured cells or Xenopus oocytes. CHT1 transports choline with a Km value of 1–5 μM in a Na + - and Cl −-dependent manner (Okuda et al. 2000).The only known specific inhibitor of CHT1 is hemicholinium-3 (HC-3), … Web10 de jun. de 2005 · In cholinergic neurons, the synthesis of acetylcholine (ACh) depends upon the reuptake of choline from the synaptic cleft by a high-affinity, sodium-dependent hemicholinium-3 (HC-3)-sensitive transporter (Haga 1971; Yamamura and Snyder 1972, 1973).Choline uptake is the limiting step for ACh synthesis, with increased choline …

Web5 de mai. de 2024 · The high-affinity choline transporter CHT1 mediates choline uptake, the rate-limiting and regulatory step in acetylcholine synthesis at cholinergic presynaptic … Web28 de mar. de 2003 · Uptake of choline by the high-affinity choline transporter CHT1 is the rate-limiting step in neuronal acetylcholine (ACh) synthesis. Here, we investigated by RT …

Web16 de mai. de 2013 · High-affinity choline uptake protein BetT: Tetragenococcus halophilus: 12172: TEH_13620: glycine betaine transporter ButA: Thauera linaloolentis: 102519: C666_13385: choline/carnitine/betaine transporter: Tsukamurella paurometabola: 16120: Tpau_2792: choline/carnitine/betaine transporter:

Web29 de jul. de 2014 · The high-affinity choline uptake activity was also shown to depend on the kind of anions and on the concentrations of K +: the highest activity was observed in the presence of Cl − and 0.35–4.8 mM K +, together with 126 mM Na + . Selective distribution and characterization of the high-affinity choline uptake system in cholinergic neurons crystal coloredWebCHT1 protein is mainly found in intracellular organelles, such as endosomal compartments and synaptic vesicles. The presence of CHT1 at the plasma membrane is limited by … crystal colored contactsWebCholine uptake (Vmax) increases up to 3 months of age and decreases significantly from 1 to 7 years of age ( Fig. 6A; Table III ). A further indication of a reduced synthesis with … dwarf fortress where to find sandWebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) crystal color changing lightWebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … crystal colored glassesWebactivity increased in response to hyperosmolarity, BetT mediated signiﬁcant uptake under low-osmolarity conditions, suggesting a role in transport for both osmoprotection … dwarf fortress where to embarkWebE. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA … crystal coloring book