WebCTSK contributes to the aggressive phenotype of CRC cells both in vitro and in vivo. Silencing CTSK or administration of Odanacatib, a CTSK-specific inhibitor, totally abolished the CTSK-enhanced migration and motility of CRC cells. Interestingly, the tumor-secreted CTSK could bind to toll-like receptor 4 (TLR4) to stimulate the M2 polarization ... Cathepsin K, abbreviated CTSK, is an enzyme that in humans is encoded by the CTSK gene.
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WebMar 29, 2024 · Clinical resource with information about CTSK, Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3., Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment., Pyknodysostosis, and available tests. There are links to practice guidelines and … WebDec 21, 2024 · To better understand Ctsk-Cre expression and ensure appropriate use of this Cre line, we performed a comprehensive analysis of Ctsk-Cre expression at the single-cell level in major organs and tissues using two green fluorescent protein (GFP) reporters (ROSA nT-nG and ROSA tdT) and a tissue clearing technique in young and aging mice. … designer draperies fl fort worth tx
CTSK Gene - GeneCards CATK Protein CATK Antibody
WebDec 28, 2024 · This study advanced a novel role for Ctsk in TLR9 and autophagy to explain the interaction between periodontitis and RA. CatK-deficiency impairs post-myocardial infarction cardiac function. his study is the first to provide molecular insights into Ctsk-regulated Haemorrhagic Transformation after cerebral ischaemia. WebJan 31, 2024 · 2、南京中医药大学附属医院骨伤科. 摘要:目的研究蛇床子素 (osthole, OST)对破骨细胞形成和骨吸收的影响,并初步分析其分子机制。. 方法体外构建破骨细 … WebHere, we examined whether CTSK participates in cancer-induced skeletal muscle loss and dysfunction, focusing on protein metabolic imbalance. Methods: Male 9-week-old wild-type (CTSK +/+, n = 10) and CTSK-knockout (CTSK-/-, n = 10) mice were injected subcutaneously with Lewis lung carcinoma cells (LLC; 5 × 10 5) or saline, respectively. … chubby scooter deck